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南京医科大学外科感染与免疫临床转化研究中心

Clinical transformation research center of surgical infection and immunity, Nanjing Medical University

最新发表论文（2023年收录）

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作者

通讯作者

出处

4-octyl itaconate as a metabolite derivative inhibits

inflflammation via alkylation of STING

李委振

任建安

cell reports

最新发表论文（2022年收录）

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作者

通讯作者

出处

Post-Translational Modififications of STING: A Potential Therapeutic Target

康佳琪

任建安

frontiers in immunology

The interaction between STING and NCOA4 exacerbates lethalsepsis by orchestrating ferroptosis and inflammatory responses in macrophages

吴婕

任建安

Cell Death Dis

最新发表论文（2021年收录）

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作者

通讯作者

出处

Current Practice of Acute Appendicitis Diagnosis and Management in China (PANDA-C): A National Cross-Sectional Survey.

吴婕

任建安

Surg Infect (Larchmt)

Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury.

刘秦杰

任建安

Cell Death Dis

Iron homeostasis and disorders revisited in the sepsis.

刘秦杰

任建安

Free Radic Biol Med

STING-dependent induction of lipid peroxidation mediates intestinal ischemia-reperfusion injury

吴婕

任建安

Free Radic Biol Med

Low-dose carboplatin reprograms tumor immune microenvironment through STING signaling pathway and synergizes with PD-1 inhibitors in lung cancer.

Zhou li

任建安

Cancer Lett

A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption.

Zou D

任建安

EBioMedicine

最新发表论文（2020年收录）

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作者

通讯作者

出处

中国腹部手术后手术部位感染的多中心横断面研究

张旭飞

任建安

中华胃肠外科杂志

Degree of STING activation is associated with disease outcomes.

胡琼源

任建安

Gut

Hypertonic saccharide solution delays pyroptosis in murine macrophages regardless of the membrane binding of gasdermin D N-terminal.

郑嘉烁

任建安，高翔，李秋荣

Eur J Immunol

Incidence and risk factors of surgical site infection following colorectal surgery in China: a national cross-sectional study

张旭飞

任建安

BMC Infect Dis.

mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion

张旭飞

任建安，吴秀文，赵云

Cell Death Dis

Early Enteral Nutrition Preserves Intestinal Barrier Function through Reducing the Formation of Neutrophil Extracellular Traps (NETs) in Critically Ill Surgical Patients

胡琼源

任建安

Oxid Med Cell Longev.

最新发表论文（2019年收录）

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作者

通讯作者

出处

中性粒细胞胞外诱捕网在脓毒症及肠屏障功能中的研究进展

胡琼源

任建安

医学研究生学报

中国慢性危重症及外科相关慢性危重症的多中心横断面研究

李思澄

任建安

中华胃肠外科杂志

中国急性阑尾炎2017年诊疗状况分析

吴婕

任建安

中华胃肠外科杂志

Damps' role in inflammatory bowel disease: A paradoxical player of mtDNA-STING signaling pathway in gut homeostasis.

胡琼源

任建安

Sci Bull

Microbiota-immune interaction in the pathogenesis of gut-derived infection.

王晨阳

任建安

Frontiers in Immunology

Hypertonic saccharide solution delays pyroptosis in murine macrophages regardless of the membrane binding of gasdermin D N-terminal.

郑嘉烁

任建安

Eur J Immunol

Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside

李思澄

任建安

Oxid Med Cell Longev.

Mitochondrial DNA in liver inflammation and oxidative stress.

张旭飞

任建安

Life Sci

Polymicrobial Bacteremia Involving Klebsiella pneumoniae in Patients with Complicated Intra-Abdominal Infections: Frequency, Co-Pathogens, Risk Factors, and Clinical Outcomes.

刘秦杰

任建安

Surg Infect (Larchmt)

Effects of Changes in the Levels of Damage-Associated Molecular Patterns Following Continuous Veno–Venous Hemofiltration Therapy on Outcomes in Acute Kidney Injury Patients With Sepsis.

吴婕

任建安

Front Immunol

STING-mediated intestinal barrier dysfunction contributes to lethal sepsis.

胡琼源

任建安

EBioMedicine

The Emerging Role of Stimulator of Interferons Genes Signaling in Sepsis: Inflammation, Autophagy and Cell Death.

胡琼源

任建安

Acta Physiol (Oxf)

最新发表论文（2018年收录）

题名

作者

通讯作者

出处

肠外瘘并发腹腔感染的病原菌分布及耐药性分析

刘秦杰

任建安

中国实用外科杂志

Released Mitochondrial DNA Following Intestinal Ischemia Reperfusion Induces the Inflammatory Response and Gut Barrier Dysfunction

胡琼源

任建安

Scientific Reports

The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway

胡琼源

任建安

Cell Death & Disease

Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

胡琼源

任建安

Oxidative Medicine and Cellular Longevity

Risk factors and clinical outcomes of hypervirulent Klebsiella pneumoniae induced bloodstream infections

李佳扬

任建安

European Journal of Clinical Microbiology & Infectious Diseases

Effects of Changes in the Levels of Damage-Associated Molecular Patterns Following Continuous Veno-Venous Hemofiltration Therapy on Outcomes in Acute Kidney Injury Patients With Sepsis

吴婕

任建安、吴秀文

Frontiers in Immunology

最新发表论文（2017年收录）

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作者

通讯作者

出处

线粒体DNA在固有免疫调节中的研究进展

胡琼源

任建安

医学研究生学报

消化道瘘切除术后血糖升高对患者临床结局的影响

胡琼源

任建安

中华胃肠外科杂志

Urinary Mitochondrial DNA Levels Identify Acute Kidney Injury in Surgical Critical Illness Patients

胡琼源

任建安

Shock

The Impact of Obesity on the Clinical Course of Inflammatory Bowel Disease: A Meta-Analysis

胡琼源

任建安

Med Sci Monit

Shifting trends in bacteriology and antimicrobial resistance among gastrointestinal fistula patients in China: an eight-year review in a tertiary-care hospital.

刘秦杰

任建安

BMC Infect Dis.

Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis

吴骎

任建安

BMC Anesthesiol

Elevated Levels of Plasma Mitochondrial DNA Are Associated with Clinical Outcome in Intra-Abdominal Infections Caused by Severe Trauma.

胡琼源

任建安

Surg Infect (Larchmt)

最新发表论文（2016年收录）

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作者

通讯作者

出处

外科感染合并血小板减少诊治进展

吴骎

任建安

中国实用外科杂志

Clinical Significance of Postoperative Hyperglycemia in Nondabetic Patient Undergoing Definitive Surgery for Gastrointestinal Fistula.

胡琼源

任建安

Surg Infect (Larchmt)

The Incidence, Clinical Outcomes, and Risk Factors of Thrombocytopenia in Intra-Abdominal Infection Patients: A Retrospective Cohort Study

吴骎

任建安

PLoS One

Preoperative prognostic nutritional index predicts postoperative surgical site infections in gastrointestinal fistula patients undergoing bowel resections.

胡琼源

任建安

Medicine (Baltimore)

Monocyte subsets and monocyte-platelet aggregates: implications in predicting septic mortality among surgical critical illness patients.

吴骎

任建安

Biomarkers

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